Effects of a Protocol Combining a Non-Irritating Shampoo and an Adelmidrol-Based Adsorbent Mousse on Seborrhoea and Other Signs and Symptoms Secondary to Canine Atopic Dermatitis: A Multicenter, Open-Label Uncontrolled Clinical Trial

Effects of a Protocol Combining a Non-Irritating Shampoo and an Adelmidrol-Based Adsorbent Mousse on Seborrhoea and Other Signs and Symptoms Secondary to Canine Atopic Dermatitis: A Multicenter, Open-Label Uncontrolled Clinical Trial

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The present study aimed at evaluating the effect of a gentle shampoo and a mousse containing Adelmidrol, tapioca stuart products emcelle tocopherol starch and a non-prescription antimicrobial complex on seborrhoea and other clinical signs secondary to canine atopic dermatitis (cAD).Forty-six dogs with cAD-associated seborrhoea and/or pruritus > 4 cm on the pruritus visual analogue scale (P-VAS) and/or bacterial/Malassezia overgrowth were enrolled.The mousse was applied twice daily, and dogs were evaluated at days (D)0, 7, 14 and optionally 28, by means of a skin seborrheic index (SSI), P-VAS, cAD lesion index (CADLI), and a semiquantitative cytological score.The mean SSI value improved during the first two weeks (4.

1 ± 0.37 to 1.9 ± 0.30; p < 0.

0001).The mean P-VAS score (cm) decreased from 6.6 ± 0.19 at D0 to 3.

8 ± 0.31 at D14 (p < 0.0001).The mean CADLI score dropped from 13.

7 ± 1.24 to 8.5 ± 1.14 at D14 (p < 0.

001).The cytological score for bacteria and Malassezia decreased from 3.2 ± 0.10 and 3.

2 ± 0.11, respectively, to 1.2 ± 0.19 and 1.

2 ± 0.24 (p < 0.0001).All the investigated signs further improved at chainsaw file D28.

Altogether, these observations suggest that the tested protocol might be useful in managing cAD-associated signs.